Right now scientific questions are chosen for study in a largely autocratic way. Typically grants for research on particular questions come from federal funding agencies, and scientists competitively apply with the money going to the chosen researcher via a peer review process.
I suspect, as the tools of online science become increasingly available, the real questions people face in their day to day lives will be more readily answered. If you think about all the things you do and decisions you make in a day, many of them don’t have a strong empirical basis. How you wash the dishes or do laundry, what foods are healthy, what environment to maintain in your house, what common illness remedies work best, who knows, but these types of questions, the ones that occur to you as you go about your daily business, aren’t prioritized in the investigatory model we have now for science. I predict that scientific investigation as a whole, not just that that is government funded, will move substantially toward providing answers to questions of increasingly local importance.